VPRIV® (Velaglucerase Alfa for Injection)

VPRIV® is a brand-name medication that contains the active ingredient velaglucerase alfa. It is primarily used for the treatment of Type 1 Gaucher disease, a rare genetic disorder in which the body lacks an enzyme called glucocerebrosidase. VPRIV® is an enzyme replacement therapy that provides the missing glucocerebrosidase enzyme to individuals with Gaucher disease. This enzyme is necessary for the breakdown of a certain type of fat in the body.

Indications and Uses

VPRIV® is indicated for the long-term treatment of adults and pediatric patients with Type 1 Gaucher disease.

Dosage and Administration

The dosage of VPRIV® is determined by a healthcare provider based on the patient's specific condition and weight. The medication is administered by intravenous (IV) infusion. The dose and frequency are individualized to the patient's needs.

Contraindications

VPRIV® should not be used in individuals with a known hypersensitivity to velaglucerase alfa or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of VPRIV® may include:

• Infusion reactions (e.g., fever, chills, fatigue).

• Headache.

• Hypersensitivity reactions.

• Abdominal pain.

• Skin reactions.

Serious side effects are rare but may include:

• Severe allergic reactions (e.g., anaphylaxis).

• Liver abnormalities.

It is crucial to report any severe or unusual side effects to your healthcare provider.

Storage and Shelf Life

Store VPRIV® at 2-8°C (36-46°F) in the original carton to protect it from light. Do not freeze. Do not use VPRIV® after the expiration date.

Packaging and Presentation

VPRIV® is available as a lyophilized powder in single-use vials for reconstitution.

Regulatory Information

VPRIV® is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on VPRIV®. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.