VONVENDI® (von Willebrand Factor [Recombinant])

VONVENDI® is a brand-name medication that contains the active ingredient von Willebrand factor (recombinant). It is primarily used for the treatment and prevention of bleeding episodes in individuals with von Willebrand disease, a hereditary bleeding disorder. VONVENDI® is a recombinant form of von Willebrand factor, which is essential for blood clotting. It is used to replace the deficient or defective von Willebrand factor in individuals with von Willebrand disease, reducing the risk of bleeding episodes and assisting in clot formation.

Indications and Uses

VONVENDI® is indicated for the treatment of bleeding episodes in individuals with von Willebrand disease. It can also be used to prevent excessive bleeding during and after surgery in patients with this disorder.

Dosage and Administration

The dosage of VONVENDI® is determined by a healthcare provider based on the patient's specific condition and the severity of the bleeding episode. The medication is administered by intravenous (IV) injection. The dose and frequency are individualized to the patient's needs and the response to treatment.

Contraindications

VONVENDI® should not be used in individuals with known hypersensitivity to von Willebrand factor (recombinant) or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of VONVENDI® may include:

• Headache.

• Fatigue.

• Dizziness.

• Nausea.

• Allergic reactions.

Serious side effects are rare but may include:

• Formation of inhibitors to von Willebrand factor.

• Thrombosis (formation of blood clots).

• Anaphylactic reactions (severe allergic reactions).

It is crucial to report any severe or unusual side effects to your healthcare provider.

Storage and Shelf Life

Store VONVENDI® at 2-8°C (36-46°F) in the original carton to protect it from light.Do not freeze. Do not use VONVENDI® after the expiration date.

Packaging and Presentation

VONVENDI® is available as a lyophilized powder in single-use vials for reconstitution.

Regulatory Information

VONVENDI® is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on VONVENDI®. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.