MOTEGRITYTM (Prucalopride)

MOTEGRITYTM is a brand-name medication that contains the active ingredient prucalopride. It is primarily used to treat chronic idiopathic constipation in adult patients. MOTEGRITYTM is a selective serotonin-4 (5-HT4) receptor agonist. It works by increasing the movement of the gastrointestinal tract, which helps to alleviate constipation.

Indications and Uses

MOTEGRITYTM is indicated for the following purposes:

• Treatment of chronic idiopathic constipation (CIC) in adults.

• It is used to relieve symptoms such as infrequent bowel movements, hard stools, and the sensation of incomplete bowel movements.

Dosage and Administration

The dosage of MOTEGRITYTM is determined by a healthcare provider based on the patient's specific condition. The medication is taken orally, typically once daily, with or without food. The dose may be adjusted over time to achieve optimal relief from constipation.

Contraindications

MOTEGRITYTM should not be used in individuals with known hypersensitivity to prucalopride or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of MOTEGRITYTM may include:

• Headache.

• Nausea.

• Diarrhea.

• Abdominal pain.

• Flatulence.

Serious side effects are rare but may include:

• Allergic reactions.

• Changes in heart rate (ECG abnormalities).

• Intestinal ischemic events (reduction of blood flow to the intestines).

It is crucial to report any severe or unusual side effects to your healthcare provider.

Storage and Shelf Life

Store MOTEGRITYTM at room temperature (20-25°C or 68-77°F). Protect it from excessive heat and moisture. Do not use MOTEGRITYTM after the expiration date. 

Packaging and Presentation

MOTEGRITYTM is available in tablet form.

Regulatory Information

MOTEGRITYTM is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on MOTEGRITYTM. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.