KAZANO (Alogliptin and Metformin HCl)

KAZANO is a combination medication that contains two active ingredients, alogliptin and metformin hydrochloride (HCl). It is primarily used to manage blood sugar levels in individuals with type 2 diabetes. KAZANO combines two different classes of medications to address the management of type 2 diabetes. Alogliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor that helps regulate blood sugar, while metformin is a biguanide that improves insulin sensitivity and reduces glucose production by the liver.

Indications and Uses

KAZANO is indicated for the following purposes:

• Treatment of type 2 diabetes mellitus in adults.

• It is used to improve glycemic control in combination with diet and exercise.

• KAZANO is often prescribed when treatment with metformin alone is not sufficient or when patients are already taking both alogliptin and metformin as separate medications.

Dosage and Administration

The dosage of KAZANO is determined by a healthcare provider based on the patient's specific condition and their response to the medication. The tablets are taken orally, typically twice daily with meals. The dose may be adjusted over time to achieve optimal blood sugar control.

Contraindications

KAZANO should not be used in individuals with known hypersensitivity to alogliptin, metformin, or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of KAZANO may include:

• Nausea.

• Diarrhea.

• Headache.

• Upper respiratory tract infection.

• Low blood sugar (hypoglycemia) when used in combination with other antidiabetic medications.

Serious side effects are rare but may include:

• Lactic acidosis (a potentially life-threatening condition), particularly in individuals with kidney or liver problems.

• Allergic reactions.

It is crucial to report any severe or unusual side effects to your healthcare provider.

Storage and Shelf Life 

Store KAZANO at room temperature (20-25°C or 68-77°F), away from excessive heat and moisture. Protect it from light. Do not use KAZANO after the expiration date. Packaging and Presentation

KAZANO is available in tablet form, with various strengths of alogliptin and metformin HCl.

Regulatory Information

KAZANO is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on KAZANO. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.