KALBITOR® is a brand-name medication that contains the active ingredient ecallantide. It is primarily used to treat individuals with hereditary angioedema (HAE) by providing relief from acute attacks. KALBITOR® is a selective inhibitor of plasma kallikrein, an enzyme involved in the production of bradykinin, which plays a key role in causing swelling and inflammation in individuals with HAE.
Indications and Uses
KALBITOR® is indicated for the following purposes:
Treatment of acute attacks of hereditary angioedema (HAE) in individuals aged 12 years and older.
It is used to provide rapid relief from the symptoms of HAE, such as swelling and discomfort.
Dosage and Administration
The dosage of KALBITOR® is determined by a healthcare provider based on the patient's weight and specific condition. The medication is administered as a subcutaneous (under the skin) injection. It is important to use KALBITOR® as soon as an HAE attack is recognized.
Contraindications
KALBITOR® should not be used in individuals with known hypersensitivity to ecallantide or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.
Adverse Effects and Side Effects
Common side effects of KALBITOR® may include:
Headache.
Dizziness.
Injection site reactions, such as pain and redness.
Nausea.
Serious side effects are rare but may include:
Anaphylactic or severe allergic reactions, which can manifest as hives, difficulty breathing, and swelling of the face, lips, or tongue.
Hypersensitivity or immune responses.
Risk of antibody formation against KALBITOR®.
It is crucial to report any severe or unusual side effects to your healthcare provider.
Storage and Shelf Life
Store KALBITOR® at room temperature (20-25°C or 68-77°F). Protect it from light. Do not use KALBITOR® after the expiration date.
Packaging and Presentation
KALBITOR® is available as a sterile, colorless to pale yellow solution in single-use vials for subcutaneous injection.
Regulatory Information
KALBITOR® is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.
References
Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on KALBITOR®. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.
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