ACTOplus Met

ACTOplus Met is a combination medication containing two active ingredients, pioglitazone and metformin hydrochloride (HCl). ACTOplus Met is a combination drug that addresses the management of type 2 diabetes. It combines the effects of pioglitazone and metformin hydrochloride to help control blood sugar levels in individuals with this condition.

Indications and Uses

• ACTOplus Met is indicated for the following purposes:

• Treatment of type 2 diabetes in adults when diet and exercise alone do not provide adequate glycemic control.

• It is typically prescribed when metformin alone is not sufficient.

Dosage and Administration:

The dosage of ACTOplus Met is determined by a healthcare provider and is often individualized based on the patient's specific response and medical history. The medication is administered orally as a tablet. It is generally taken with meals to reduce the likelihood of gastrointestinal side effects.

Contraindications

ACTOplus Met should not be used in the following situations:

• Known hypersensitivity to pioglitazone, metformin, or any of their components.

• Patients with heart failure or a history of heart failure.

• Severe renal impairment (creatinine clearance below 30 mL/min).

Adverse Effects and Side Effects

Common side effects of ACTOplus Met may include:

• Gastrointestinal symptoms such as diarrhea, nausea, vomiting, or abdominal discomfort.

• Weight gain, often related to pioglitazone.

• Edema (swelling), particularly in the legs and ankles.

Serious side effects are rare but may include:

• Lactic acidosis (a rare but potentially life-threatening condition) related to metformin use. Symptoms can include muscle pain, rapid breathing, or stomach pain.

• Liver problems, which can cause yellowing of the skin or eyes, dark urine, or abdominal pain.

• Heart problems, especially in patients with pre-existing cardiovascular issues.

• Any side effects or concerns should be reported to your healthcare provider.

Storage and Shelf Life

Store ACTOplus Met at room temperature (20-25°C). Protect the medication from light and moisture. Check the expiration date on the packaging and do not use if expired.

Packaging and Presentation

ACTOplus Met is typically available in tablet form, supplied in blister packs or bottles, with each containing a specified quantity of tablets.

Regulatory Information

ACTOplus Met is subject to regulation by health authorities in most countries. It is crucial to use this medication as directed by a healthcare professional and in accordance with local regulations regarding packaging, labeling, and dosage instructions.

References

Always consult with your healthcare provider and refer to the drug's official prescribing information and product labeling for the most up-to-date and comprehensive information on ACTOplus Met. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.