GATTEX® (Teduglutide) for Injection

GATTEX® is a brand-name medication that contains the active ingredient teduglutide. It is used to treat adults with short bowel syndrome (SBS) who are dependent on parenteral nutrition (PN). GATTEX® is a synthetic analog of a naturally occurring human hormone called glucagon-like peptide-2 (GLP-2). It works by promoting the growth and repair of the lining of the small intestine, increasing its absorptive capacity and reducing the need for PN.

Indications and Uses

GATTEX® is indicated for the following purposes:

• Treatment of adults with short bowel syndrome (SBS) who are dependent on parenteral nutrition (PN).

• It is used to reduce the need for PN and increase intestinal absorption of fluids and nutrients in individuals with SBS.

Dosage and Administration

The dosage of GATTEX® is determined by a healthcare provider based on the patient's specific condition. The medication is administered as a subcutaneous injection. The dose and frequency of administration are individualized to the patient's needs.

Contraindications

GATTEX® should not be used in individuals with known hypersensitivity to teduglutide or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of GATTEX® may include:

• Abdominal pain.

• Nausea.

• Vomiting.

• Headache.

• Upper respiratory tract infections.

Serious side effects are rare but may include:

• Gastrointestinal malignancies (cancers) which have been reported in patients treated with GATTEX®.

• Polyps in the colon.

It is crucial to report any side effects, especially severe or unusual ones, to your healthcare provider.

Storage and Shelf Life

Store GATTEX® in the refrigerator at 2-8°C (36-46°F). Do not freeze. Protect it from light. Do not use GATTEX® after the expiration date.

Packaging and Presentation

GATTEX® is available as a sterile powder for reconstitution in vials for subcutaneous injection.

Regulatory Information

GATTEX® is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on GATTEX®. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.