FEIBA® (Anti-Inhibitor Coagulant Complex)

FEIBA® is a brand-name medication that contains Anti-Inhibitor Coagulant Complex. It is used to treat bleeding episodes in individuals with hemophilia A or B who have developed inhibitors to traditional clotting factor replacement therapies. FEIBA® is a complex mixture of clotting factors, including factor VIII and factor IX, as well as other proteins involved in blood clotting. It helps replace the missing or deficient clotting factors and control bleeding in individuals with hemophilia and inhibitors.

Indications and Uses

FEIBA® is indicated for the following purposes:

• Treatment of bleeding episodes in individuals with hemophilia A or B who have developed inhibitors (antibodies) to factor VIII or factor IX.

• Prophylactic (preventive) therapy to reduce the frequency of bleeding episodes in individuals with hemophilia and inhibitors.

• It is used to control and manage bleeding episodes in individuals with congenital hemophilia who are not responding to traditional factor replacement therapies.

Dosage and Administration

The dosage of FEIBA® is determined by a healthcare provider based on the patient's weight, the severity of bleeding, and the specific condition. The medication is administered intravenously (IV) under the supervision of a healthcare professional. The dose and frequency of administration will vary based on the patient's needs.

Contraindications

FEIBA® should not be used in individuals with known hypersensitivity to any of its components or bovine-derived products. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of FEIBA® may include:

• Fever.

• Headache.

• Rapid heartbeat.

• Nausea.

• Diarrhea.

Serious side effects are rare but may include:

• Thrombosis (formation of blood clots).

• Disseminated intravascular coagulation (DIC), a complex clotting disorder.

• Allergic reactions, which can manifest as hives, difficulty breathing, and swelling of the face, lips, or tongue.

It is crucial to report any side effects, especially serious or unusual ones, to your healthcare provider.

Storage and Shelf Life

Store FEIBA® at 2-8°C (36-46°F) in the refrigerator. Do not freeze. Protect it from excessive heat. Do not use FEIBA® after the expiration date.

Packaging and Presentation

FEIBA® is available as a sterile lyophilized powder for reconstitution.

Regulatory Information

FEIBA® is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on FEIBA®. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.