ENTYVIO (Vedolizumab)

ENTYVIO is a brand-name medication that contains the active ingredient vedolizumab. It is used to treat chronic inflammatory bowel diseases, such as Crohn's disease and ulcerative colitis. ENTYVIO is a biologic medication that targets specific molecules involved in the inflammatory process within the gut. It is designed to reduce inflammation and help manage the symptoms of chronic inflammatory bowel diseases.

Indications and Uses

ENTYVIO is indicated for the following purposes:

• Treatment of moderate to severe Crohn's disease in individuals who have not responded well to conventional therapies.

• Treatment of moderate to severe ulcerative colitis in patients who have not achieved an adequate response with other treatments.

• Management of the symptoms and complications of these chronic inflammatory bowel diseases.

Dosage and Administration

The dosage of ENTYVIO is individualized based on the patient's weight and the specific condition being treated. The medication is administered through intravenous (IV) infusion in a healthcare setting. The frequency and duration of treatment are determined by a healthcare provider.

Contraindications

ENTYVIO should not be used in individuals with known hypersensitivity to vedolizumab or any of its components. It is essential to discuss any allergies or potential reactions with a healthcare provider.

Adverse Effects and Side Effects

Common side effects of ENTYVIO may include:

• Headache.

• Upper respiratory tract infections.

• Joint pain.

• Nausea.

• Fatigue.

Serious side effects are rare but may include:

• Serious infections, which can manifest as fever, chills, or persistent cough.

• Hypersensitivity reactions, including hives, difficulty breathing, and swelling of the face, lips, or tongue.

• Liver problems, which may be indicated by yellowing of the skin or eyes, dark urine, or abdominal pain.

It is crucial to report any side effects, especially severe or unusual ones, to your healthcare provider.

Storage and Shelf Life

Store ENTYVIO at 2-8°C (36-46°F) in the refrigerator. Do not freeze. Protect it from light. Do not use ENTYVIO after the expiration date.

Packaging and Presentation

ENTYVIO is available as a sterile solution for IV infusion in vials.

Regulatory Information

ENTYVIO is subject to regulation by health authorities to ensure its safety and efficacy. It is essential to use this medication as directed by a healthcare professional and in accordance with local regulations.

References

Always consult with your healthcare provider and refer to the official prescribing information and product labeling for the most up-to-date and comprehensive information on ENTYVIO. Your healthcare provider will guide you in the proper use of this medication, monitor your progress, and tailor the treatment to your specific medical condition.